Researchers in Finland and Germany have developed an open-source software which will make it easier to process bio imaging data. The software, named BioImageXD, will help in analysing cell and tissue functions.
Among other things, the BioImageXD software is a tool for analysing how molecules move on cell surfaces and how they bond together.
With the software, scientists can analyse the composition of cell surfaces, study how cancer cells spread in a three-dimensional environment, or measure how effectively viruses and targeted drugs enter cells. Such calculations have not been possible before.
In recent years, cell and tissue imaging with new specialised microscopes has considerably advanced research in bioscience and biomedicine. The new methods also allow for studies on living cells.
To meet the need for software which will render the microscopic images into three-dimensional models, researchers in Turku, Jyväskylä and Dresden developed BioImageXD.
One of the unique features of the software is that it can be used to create completely new analysis methods even for users who do not possess programming skills. It can also process thousands of images at the same time and analyse millions of molecules.
Comparison tests have shown that BioImageXD is faster and more sensitive than other similar programmes.
The BioImageXD software will be featured in a special issue of Nature Methods, focusing on the processing of biomedical images.
The work to develop the software has been funded by the Academy of Finland, the European Union and Tekes, the Finnish Funding Agency for Technology and Innovation.